Preliminary In-vivo study on rats to enhance recognizing the use of Anacyclus clavatus as traditional diet by the local population from TiziOuzou

Journal of Food and Clinical Nutrition is published an article titled as “Preliminary In-vivo study on rats to enhance recognizing the use of Anacyclus clavatus as traditional diet by the local population from TiziOuzou”. Here we want to explain short note on an article.

Anacyclus clavatus is a common perennial plant belonging to the Asteraceae family. It has been known since the antiquity for its medicinal properties. This Mediterranean species is very common throughout Algeria. It has a very short vegetative cycle blooming between April and June. Nevertheless, it is spontaneous along the roadsides, removed land, dry nitrophilous grassland, up to 1,600 meters above the sea. It is an aromatic plant, and it is characterized by a specific odor.

This species has undergone several chemical investigations, indicating the presence of many types of secondary metabolites, including triterpenes, steroids, coumarins, lignans, polyacetylenes (alkamides) and flavonoids. The information gathered during our own ethno-botanical survey carried out during February and March of the year 2016 in several sites in Algeria constitutes an inventory which contributes, on the one hand, to the knowledge of the medicinal flora and, on the other hand, to a safeguard of the know-how of local populations.

Enough evidence has been accumulated in this study to show that the antiinflammatory activity of this plant is attributed to its richness in bioactive substances. In fact, the aerial part (leaves and stems) contain flavonoids (cathechin, quercetin, benzoic acid), tannins, gallic tannins and alkaloids), but in different proportions. This richness in these compounds gives it important pharmacological properties, hence their use in traditional medicine. On the other hand, this plant is devoid of anthocyanins, leuco anthocyanin, saponosides and glycosides. Similar findings were already reported for the same metabolite from A.clavatus by Aliboudhar.

The data obtained in the present study show that the aerial parts (leaf and stems) of A.clavatus used as traditional diet by the local population from Tizi-Ouzou has a highly functional quality thanks to its biochemical composition and pharmacological properties. The effects of the water extract of the aerial parts of A.clavatus on rats are numerous. First, it not only causes the total disappearance of inflammatory cells (gastric ulcer) with its anti-inflammatory activity, but it also reduces cholesterol levels and cholesterol HDL. Second, thanks to its hypoglycaemic activity it allows the reduction of glucose levels in blood.

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